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Highest Quality | For Research Use Only

Buy Tesofensine Peptide Ireland

Tesofensine is a serotonin noradrenaline dopamine reuptake inhibitor (SNDRI) from the phenyltropane family of drugs. It was originally developed for the treatment of Alzheimer’s and Parkinson’s disease, but it lacked efficacy for these conditions. However, it has shown potential in the treatment of obesity due to its ability to suppress appetite.

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Potential Benefits of Tesofensine

  • Triple Monoamine Reuptake Inhibition: Research suggests Tesofensine acts as a serotonin-noradrenaline-dopamine reuptake inhibitor (SNDRI), thereby increasing the availability of these neurotransmitters in the brain [1].
  • Appetite Suppression: Studies indicate the peptide primarily works on the hypothalamus, an important area for appetite regulation. This action enhances satiety signals, leading to reduced food intake [2].
  • Efficacy in Weight Loss: A Phase II trial demonstrated significant weight loss in obese patients treated with tesofensine, showing a mean weight loss of 12.8 kg at the highest dose over 24 weeks [3].
  • Role in Research: Tesofensine exemplifies a novel approach to obesity treatment by targeting neurotransmitter systems. While it has shown promising results, it’s still not approved for clinical use, indicating its current role is mainly within research settings [3].

References

[1] https://www.sciencedirect.com/ science/article/abs/pii/S0924977X13003003

[2] https://www.researchgate.net/ publication/44608733

[3] https://onlinelibrary.wiley.com/ doi/pdf/10.1038/oby.2011.197

 

DISCLAIMER: We do not supply peptides to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY in the process of laboratory research by responsible trained and professional individuals. All products listed on this website (https://ireland.direct-peptides.com) and provided through Direct Peptides are intended for laboratory research purposes only. The products listed on this website are NOT for human or animal consumption or ingestion of any kind.