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AMPK 2mg Pre Mixed

£24.14£67.42

AMP-activated protein kinase (AMPK) is a critical energy sensor in cells, playing an essential role in regulating cellular energy metabolism. Its activation can lead to reduced glucose levels, as evidenced in studies involving obese mice. Furthermore, AMPK signalling has been found to be modulated affecting Amyloid-β Peptide Metabolism which suggests potential implications in the management of neurodegenerative diseases like Alzheimer’s disease.

Pre Mixed Cartridge and Kit:
* 
1 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
* 1 x Peptide Cartridge Pen
* 1 x Pen Carry Case
* 3 x Pen Needle Tips

Single Mixed Cartridges (1,2 & 3) Come with:

* 1,2 or 3 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
* 3 x Pen Needle Tips
The single 1,2 & 3 cartridges do not come with a kit.

Buy 10 and get 10% Discount

490 in stock

Description

AMPK Pre Mixed Peptide 2mg  Ireland

This product is intended for research purposes only. To be used by trained professionals only.

AMP-activated protein kinase (AMPK) is a vital energy sensor in cells, playing a central role in the regulation of cellular energy metabolism. As a metabolic sensor, AMPK is involved in several essential biological processes that maintain cellular energy homeostasis. Interestingly, recent Ireland studies have shown that AMPK activation can have significant therapeutic implications.

A study published, highlighted the potential of an adiponectin peptide (APNp) in alleviating oxidative stress and NLRP3 inflammasome activation after cerebral ischemia-reperfusion injury by regulating the AMPK/GSK-3β pathway. This suggests that AMPK pre mixed peptide modulation could be a promising strategy for mitigating the neurological damage caused by stroke [1].

Further Ireland research into the role of AMPK pre mixed peptide in neurodegenerative disorders, such as Alzheimer’s disease, has shown that AMPK activation by resveratrol promotes autophagy-dependent degradation of amyloid-β peptides. This suggests that AMPK activation could potentially slow down the progression of neurodegenerative diseases [2].

In a different context, a study published showed that AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes. This indicates that AMPK might play a role in cardiovascular health and could be a potential therapeutic target for diseases such as diabetes [3].

Furthermore, research highlighted how AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance in both the hypothalamus and peripheral tissues. This underscores the importance of AMPK pre mixed peptide in maintaining body weight and energy homeostasis [4].

Additionally, another study demonstrated that hypothalamic AMPK activity is influenced by anorexigenic peptides, which inhibit food intake to maintain energy homeostasis and body weight. This further emphasizes the crucial role of AMPK in metabolic regulation [5].

Shop the full the range of AMPK peptide here.


References:

[1] https://www.sciencedirect.com/ science/article/pii/S00219258 20873062

[2] https://pubmed.ncbi.nlm.nih.gov/ 20852062/

[3] https://journals.physiology.org/ doi/full/10.1152/ajpheart.00210. 2014

[4] https://onlinelibrary.wiley.com/ doi/full/10.1111/eci.12996

[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5103348/


Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

AMPK HPLC 2023 Certificates_DIRECT PEPTIDES

 

 

 

 

 

 

 

 


ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Ireland Direct Peptides website: https://ireland.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.


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