L-37 (cap-18) 5mg Product Description – Direct Peptides
LL-37 Ireland , also known as CAP-18 (Cathelicidin antimicrobial peptide 18), is a 37 amino acid cationic peptide. It is a scientifically proven antimicrobial peptide that gets rid of various pathogens with the inclusion of bacteria, viruses, fungi, and parasites.
LL-37 is recognised as the single most human cathelicidin peptide, contained in lysosomes of macrophages. LL-37 is produced by a variety of cells, including neutrophils, monocytes, mast cells, and epithelial cells. It’s then stored in them as a propeptide that can be taken up by enzymes.
As an amphipathic a-helical peptide, LL-37 impacts the planktonic bacteria alongside the pathogens living in biofilms, fungi, or viruses like HIV that live in biofilms.
Benefits of LL-37 (cap-18) Ireland
•LL-37 has shown promising results in the prevention of uncomplicated infections. It will also defend your immune system against systemic pathogenic attacks that cause inflammation.
•LL-37 also has cytotoxicity against bacterial and healthy eukaryotic cells, which helps keep infections at bay. Moreover, it has antimicrobial functions that enable it to be used for immunomodulatory roles.
•In the case of infected monocytes, LL-37 has properties that suppress the release of pro-inflammatory cytokines like TNF-α and IL-6. As a cationic antimicrobial peptide, this amino acid can do away with a variety of pathogens
•Alongside its antimicrobial properties, LL-37 also takes part in the initial stages of innate and adaptive immunity. This is because it controls the production of cytokine and chemokine that are essential for healthy immune system functions.
•It also helps regulate autophagy in connectivity with vitamin D.
•LL-37 triggers angiogenesis and helps with the speeding up of wound healing.
•When LL-37 activates FPRL1 and P2X7, it prevents bacterial infections, so, suppressing neutrophil apoptosis. This is beneficial as your immune system can resist bacterial invasion effectively.
•While LL-37 is considered a chemotactic agent for neutrophils, monocytes, and T cell, it is also cytotoxic towards mammalian cells.
That is all there is to know about the amino acid. What is clear is that LL-37 is widely recognised for its antimicrobial properties. As a result, most individuals rely on amino acid because it has many features that can improve the quality of life significantly.